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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339b06de58b2afd72d30514ee87a752cb90a1e15cb99b523c76fc46b0c1c6708' 
  AND token = 'WSER74sC5IJ69Pp0R4J6054jkwydtKE/manzJy7pGUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}