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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680c3eac9e34b99f6c1eac09af69833cbd33da476a07ed8c552c5e04a1be86c4' 
  AND token = 'TCN/4xuMGsIIc0XXHO7ujS9VTAgxi5JeEY3XErT11gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}