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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a10808a011eadf76e4151a0d4870942e3f10b579cf5137f85c056e2430f31c' 
  AND token = 'Z2VT7z91SlB13/XMq4cnTbiiWgsPi2Cr3/NFoohIEBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}