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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14121bbc80e06f28cb4c87a7c78a108f77697836ac3cbdb9441ab0aa25a7416e' 
  AND token = 'QPon8JXDt7lztyudHCZKwxnv1bsQ096SF8Oar93IUz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}