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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf273725c31defdc8c7727a7fcf97e6e6b4201c474ba5d274cfb2b07c78cdb4' 
  AND token = 'wToVHqpURX2yFwTaCNl2ryWeiTgAU+uVSsQh16WMh8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}