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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e40940b1d74a40c7463be405a3546f7df2ead1db76319aa646dd277bb75f116c' 
  AND token = 'KxTQZqYoTxUhIFTsfMm0TVioBA5wZQuB84gWtPs1Afc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}