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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd582e1674f8858ecf721f383d09d692460ae2dbe3e77966fc4744350908c9da' 
  AND token = 'LkYRRHQ+GTSfNmrlX5YRlOAGHpkVQUlWvzTsxCxtLas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}