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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d56dc060e56e50d5c7573931009cb270b95995fa6b249e4a3e5bc3601279d77' 
  AND token = 'TLnYvQq7pvtSEP+s0QBaZpJSies0SQx57vrbAM+20Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}