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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bfe55551d41c2a23da066b5ab50979cd8b528d019f37918b8e42474b72222aa' 
  AND token = 'l/Bhauo5baBGxDnxv+9efXZLtiK4Zc/yztfxpbsHeBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}