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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7149684d8aa6d5e6867412138d146a48a16911ffb8330459cad54a9798716225' 
  AND token = '7tZMNxyIEzr4Z1psoQBDj1ItdWCYhN1KR7bsJMpre4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}