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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412a07d8f35befa1d2e5c58bcf41ea99069fcfd71b016b0de04cda84005a52d9' 
  AND token = 'DYt8l+zzcQN4OaEo1x5RSvjhf/8C56IHXdCUt6ijV98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}