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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8dec24ef677519bcbb525e01836b389fd29493878b8b7a1dcd2847f6bbe091a' 
  AND token = 'tcUJe/l5+0fJNfua/1pfujoekSloHt6tjUOEvJuNpgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}