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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa8808be64b4c55c9281eb7490ff2350c330cc3af1077c7ffb3cf95a9609b6b1' 
  AND token = 'zauw4kpRIlt+2MVkGZsB44MigXSjPwgAVEUeM60Rj7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}