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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8dc1498cfda4571bf1298564a0688d6216c59ccf69a8e61b66ba448bbfeb9a1' 
  AND token = '25OYyLy1NGwjDTHzU2inJQOKQ0bF/FRiBPrZwBRLDIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}