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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ddd6c420c19e42dc496b803cdb1e3f1a8191945816e87f4451c9ecbfcc9209a' 
  AND token = 'QwRRgQUX2O16ruizhIeEKUk+8UVl3kg5juatYSyOgyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}