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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7682a96132bce79a03ede16af49f0335c8c9b95da50b0c21b8dd1d0fe47737' 
  AND token = '2CGTcHLfWHX51GPm5fUo1XhEUw+xQo4Mc7ffhKh/8TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}