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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1e4f83c30cb13b4dd84a88184ff60afa2748167b16ce4e3f984453599e0297' 
  AND token = 'E1rQgWQS3JW5nr0m/6l1cebwwlDwBJ6T7tgGZLCGe9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}