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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd91a217fba85608c3fe17cda002d365b43f620fbac6048d0572101373622df' 
  AND token = 'ClR4j06k8+ZBLvzK5R9D76SWAiGC1wFo8x1EtOdBj4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}