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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acce7b3359fb20cd727f25a0934a55e63a17c6bcc5538dec705736c7ab8d730' 
  AND token = 'Si4iVPTQWs3hk6XVBx7FmBVEWOjOa7waWysEht0At18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}