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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb9385a0184e2cf0918ef099cedf496b5471d5eed32f239d9d9c89483210f0d' 
  AND token = 'HrQU1KolFDyasmGA9Knt1GY2Mlj5WIG7DdRsK1rsHLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}