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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b2d5c04d96589b3bc15eea8b9e4aa9d05d5b956f1c90aead042014d8479f2ab' 
  AND token = 'Pm59U/ioEXzaR3AuuGtR4GIxRcX0jMiiTtcPqxbPmuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}