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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650fb0786f775165cd6036c93e9a10ae2af0873a0276bc3a15c72d2cdd342973' 
  AND token = 'kWfUj/5UeyHFDjbt1n+EtQ9x3y3xtl11NXvB7Ix7338=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}