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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a99654b018dd6907ab40a17cb5bb76c961fcef14b0addc2c9418dbf368ca74e2' 
  AND token = 'MGp7a3W/i7aAYy0at1iATGVisIa+WhF7TjjbNhugwOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}