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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7abcf01762c481ae4eb15821296cbe85f203a15c4f3a9085aad136001ac2b125' 
  AND token = 'bkE3X5Wn6S6GvEc43bWD+Cm7Toenph8UAAOoy13AyrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}