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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f889115dfd756434b325d6e26406e003e970dc59e0161792abe4e2159b9c9f0c' 
  AND token = 'tbjv72hrW6tzsFQ1FpbELcoNfVVT0N/9dxFDsdEW19U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}