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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3343e157e903f9d09ecfa07dfb2c77e4c9a3b775432dd34a68ae99454c0db4' 
  AND token = 'TJWpU2abs1xoVRWcSXIWR7gyt46Eyjd+t04Ij603Cw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}