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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649507331e6321a130e76bca69d638889406b1463f65c05569aeb00ecb5aef60' 
  AND token = 'HeL7IISmoFq9IaCDCCDweHQv7wxJLMPBLQrnrSybAN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}