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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c52bc116e84b278495d2588d4fc037b21b23356ec4f10259ede8828ea00ca7a' 
  AND token = 'ptRIOONvkCVuwDTluE+MOpjZNNdlyW/IBA5KISx7Rks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}