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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1faaa09d6ee721b3925f010b99436e357c71f3b7d4312fcb987f37b941b2934' 
  AND token = 'RfxRislkT/a0dWP4GNiQXYGSpSxA3X/BCGXoCQg1A+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}