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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c8c099861426730a19bdd3db152470d40bebfbd4dc029c427e381929ce2545' 
  AND token = '61rlo2SNhppudS6vJexeHB9HG0TtFVaEqKsEGj+Iz6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}