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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1928c3bb61a1ceb994212e389ae62f2054a1c314d265dcf218f603b1ce914b2' 
  AND token = '1LX2c//V5A9VeWeNVbKvDfyUQPoH6ufsh3AE03Vywo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}