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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43e759fd1aa9941d9359dc672186a8182eff0f3086f92b5a21ffe2d4abcfe8d' 
  AND token = '5WHo+qvEPjfhT2sX9q1m9z5BVKmL6vi3OW1uz8f6suE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}