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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c5949bd24526a99db11fe4b94d0a4289ee17dd8ce8afe58549558b665e8c7b' 
  AND token = 'SuuJDXFx6y+v9byU547JBecD5lSyZK/zd9XP6ajJ9kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}