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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1781d1a8f322e6bea16eba940709fa1442a8b0e45df498709ae069f7f1b245c2' 
  AND token = 'w7g62kSdvJaYsFVedcwbUGJU8EQDz3IBQXf/XzApwM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}