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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d3925a67fb276c1eea6c456f21cd9c04f21e86fa37c9776df47c8497b5e01b' 
  AND token = 'DlNIw4xcMdR2cVPNrpAgJbOKbloa1p9R60mdha/birc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}