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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0bba17a14006ef08fd6924f1368a95839ea389ea89008e900528bc176bb4dfa' 
  AND token = '9crXp1uXHsxmAPZQIcaG11YKTvoCQf9ii8TJiRa9UXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}