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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fd4a2575f40fa94c4e96699a16d3e221860ce941699e7675b512db180b1679f' 
  AND token = 'vMarLjmIkrdjhIihNyMXlcogV6GSypzQQ6x7TGXEJIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}