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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd91c1f349a3c1e9fe8dd886a35540188647502006072740d518e8d3e8d4966d4' 
  AND token = 'zj4iwQ2Xrzk4mor2I1Sck1QAS85XwS1KalAueAnVIGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}