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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8654cf4430638454332afa284cd941d1d5aaaaa9d1e27266cb40500c1796a1e3' 
  AND token = 'UPZsmI/o0Cfgs0trCNNAxUfylR4zhZj0Ex2LCf4W3RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}