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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9a397c58362817080e42c1513f4d356e3d820a4e0d631d255a61faa4e1c710' 
  AND token = 'ZHnxBP6S5JtC8z46LfItl6KM4wcbvy2L7Hw9aF3fdAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}