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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32bdf617c26e1c9679eb61f54d4271882fa9fc4395d96e6665dbfbd27700804d' 
  AND token = '1EQlG6l1RP3tp48XJ7O6vRkpIxjHB5sWGfYJ1E1cFXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}