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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4b8d7e4073624b441adb58f1a10f2b166d69e3a3684c76e30c5991d1a7e322' 
  AND token = 'GoBXq1+qjACFHd699+rYuohTois2VWXNrLk/eE9a618=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}