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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1450b79aba161c7a160e184eb8ba07496758b6a4177c8bd2b2a27604e2c9eee8' 
  AND token = 'nPzwswwWkP3m7peBRRlPFMWVeSxrIZab3bGXu51K+Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}