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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53776cb9a8d0696dcae17d1b59d9de46d9ab73a4192425caa2673163b4b5908' 
  AND token = 'fIKnB8TH+uIiS0stmYz1Bihpsj4PRnOgJ6jrz3Q2Ioc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}