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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd001d66b17dacc0ec1cc3682587401287fba749b3c03b5178e371095502f0991' 
  AND token = 'S3FLPM+nfSzS0DIf8q2CJcuyb09SRETRQUY/XrMQ+Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}