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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd173b87675b21ff11385ef1851d803c02b92a4fa3da8680f12d31db37d005e36' 
  AND token = 'b+mmaibiqnihYPunM8KXOKyHn9E/9XPscreFgtywFdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}