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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c6caea0c484530c8d82e566fa8d8d5003b4c738b0d03085b5724c6d189ad8e' 
  AND token = '7Y1FtgIh1VJRGx4kVKrn7L6WQhIsyGKmqW1yVG0Eur4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}