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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff0343259f2f45c44ea26cc4c5a603c10f1a50d44c90d78b3cbcf759c0c91aa' 
  AND token = 'vJx0s9JFuGvwBTOp3/MgE7MD68oAO9+Tc3xx/TguTWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}