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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e164d8f65dfdf77e73455b66eda96575d5d35b0a50dba0c3509c3b309190ceba' 
  AND token = 'r4X/ypSBXItrZMxKU1ksU9xx47D4YaA5IUfo9sDDyn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}