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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad6224ab6a4999ce28506b1d62064139bc45a0d32c2bbbc08ffbdba87a7d2d4' 
  AND token = 'Hm0u/lOkesxrrTQ+isdQs4FIp52fPdh7SK17fA8heLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}